Document Details

Document Type : Article In Journal 
Document Title :
Lateralized Postictal EEG Delta Predicts The Side of Seizure Surgery in Temporal Lobe Epilepsy.
تخطيط الدماغ بعد حدوث التشنج القادم من الفص الجانبى .
 
Document Language : English 
Abstract : Purpose: The concordance of lateralized EEG postictal polymorphic delta activity (PPDA) to the side of seizure origin in temporal lobe epilepsy (TLE) has received limited study. The objective is to study the lateralizing value of PPDA in patients with documented TLE. Methods: A cohort of consecutive adults with TLE, detailed presurgical evaluation before temporal lobectomy, and minimum follow-up of 2 years were included. One author masked the ictal rhythm of presurgical EEGs and randomly presented 20 seconds of preictal and the postictal EEG to two electroencephalographers (EEGers) who were blind to all clinical data. They independently assigned PPDA to 1 of 3 categories: not present, bilateral, or lateralized (defined as newly appearing or an amplitude more than 50% of the preictal record). Results: 80 seizures from 29 patients were studied. 15 patients had a left and 14 had a right temporal lobectomy. 23 patients were seizure free or substantially improved (defined as simple partial or nocturnal seizures only). Lateralized PPDA was present in 64% of all EEGs and at least 1 record from 22 patients (76%). Lateralized PPDA, when present, was concordant with the side of surgery in 96% of the EEGs. The two EEGers agreed on the EEG findings in 73 of the 80 seizures (kappa=0.88, 95% CI 0.80-0.97). Conclusions: Lateralized PPDA is highly predictive of the side of ultimate temporal lobectomy, and by inference the side of seizure origin. The inter-rater reliability of the lateralized PPDA, using our strictly defined criteria, was excellent. 
ISSN : 0940-5429 
Journal Name : Canadian Journal of Neurological Sciences 
Volume : 3 
Issue Number : 42 
Publishing Year : 2001 AH
2001 AD 
Article Type : Article 
Added Date : Saturday, March 13, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
محمد جانjan, Mohammed ResearcherDoctorate 

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